Anastrozole: effectiveness, reviews.

Anastrozole is an anti-estrogen drug that comes in tablet form. Anastrozole was originally developed to treat breast cancer. However, in today’s medical practice, the drug is practically not used. In sports, anastrozole has gained immense popularity: it is used by athletes and strength athletes. The drug helps prevent gynecomastia, that is, the development of mammary glands, relieves swelling and other negative side effects that are often associated with taking anabolic steroids.

Anastrozole has a significant effect: just one milligram of the active ingredient can reduce circulating estradiol levels by 80%! Even tamoxifen, which is extremely popular with bodybuilders, cannot compete with anastrozole in terms of strength. overdose of tamoxifen However, drugs have different principles of action, so the comparison between them is probably not accurate.

Read more about few things about Deca

What are the effects of Anastrozole?

Anastrozole has the following effects on the body:

  • reduces the degree of aromatization (approx. 80%).
  • It has inhibitory properties.
  • Reduces estrogen levels in the blood.

One of the main features of the drug is a fairly quick result. The maximum concentration of the active substance in the blood is observed just a few hours after ingestion. In this case, the aromatization process is suppressed as quickly as possible. Because of this, Anastrozole is considered one of the most effective drugs for athletes prone to aromatherapy.

See info about steroid cycling

Type of use Anastrozole

Anastrozole is recommended only for experienced athletes: beginners are advised to refuse it. The tablets are used after the anabolic steroid is over. Anastrozole should be taken in two cases: when serious side effects appear prophylactically after taking steroids and before starting the course. After the course, the steroid is taken from 0.25 to 1 mg per day. Before the course, the dosage should be determined by a specialist.

You can take Anastrozole for two weeks: during this time the drug has time to fully show its properties.

In order for the active ingredient to get into the bloodstream as quickly as possible, anastrozole should be taken with plenty of water before meals.

Anastrozole is not recommended for female athletes. The drug can cause sudden changes in the hormonal background, which can lead to unpredictable consequences for the female body.

Read more about different type of anti-estrogen

What are the side effects of taking anastrozole?

Side effects of the drug are relatively rare. As a rule, it is associated with intolerance to the active substances or exceeding the recommended dose. The most common side effects include fatigue, drowsiness, rash, headache, as well as various negative symptoms of the gastrointestinal tract (nausea, vomiting, diarrhea, etc.).

In chronic diseases of the cardiovascular system, anastrozole should be discontinued. Because the drug actively fights the side effects of taking steroids, but at the same time inhibits the production of “good” cholesterol, which can lead to heart problems. Therefore, before taking Anastrozole, athletes with diseases of the cardiovascular system should consult a doctor or prefer drugs with a similar effect, but a different mechanism of action in the body.


The drug is very popular among athletes due to its strong antiestrogenic effect. In fact, the effect of the application can be seen just a few hours after taking the pill. The most positive reviews about Anastrozole are left by professional bodybuilders. They believe that the drug copes well with the increased production of estrogen, which is observed after a long use of anabolic steroids. However, the drug should be used very carefully: before you start taking it, you should consult your doctor. In addition, it is important to strictly adhere to the recommended dose of Anastrozole.

Post cycle therapy (PCT): goals and drugs used

After an anabolic steroid cycle, PCT or Post Cycle Therapy is required to restore the body’s natural hormonal background.

Read also about use of Trenbolone Acetate

I have to say right away that there will be a loss of muscle mass in any case. The natural level of the sex hormone testosterone is many times lower than the course. Exogenous production is around 50-130 mg per week. Some use up to 1000 mg or even an order of magnitude higher. These hormones are responsible for the body’s ability to build and maintain excess muscle mass. The loss of muscle mass after the course is directly proportional to the doses of AS (anabolic steroids). The higher it was, the stronger the “undo”.

Read more about Less Adverse Side Effects

After a cycle of Testosterone (or drugs like Turinabol, Methandrostinolone or “Methan”, Propionate, Nandrolone Decanoate or “Deca”, Donabol, Sustanon or “Sust”, Boldenone, Stanozolol) the main purpose of PCT should be clear. Not to “dry out” as some would like, or to build a little more muscle or even save. Post Cycle Therapy is designed to maximize the loss of gained muscle mass.

Read also abot post-cycle oestrogen production

The main tasks that PCT solves after the AS course

For an effective recovery, you must:

  • Resume normal testosterone synthesis as quickly as possible and reduce levels of female hormones (estrogen), which will be higher than normal in the postmenopausal period due to increased aromatization of testosterone, i.e. natural conversion to estradiol.
  • Restoration of libido and spermatogenesis.
  • Lower cortisol levels by reducing your exercise volume, workload, and physical activity. In the period after classes, the body weakens and cannot recover with the same force as when taking medication. Without reducing the load, you just “burn” your muscles.

To start PCT after a steroid cycle, you must first wait for the artificial hormone to leave the bloodstream. To do this, we take into account the periods of deterioration of various drugs. For example, this period is a maximum of 2-3 days for methane, stanozolol or testosterone propionate, with a delay of 2-3 weeks for enanthate, susta or deca.

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Preparations for PCT

Next I will explain how and why the different PCT formulations are used.

Clomid (clomiphene citrate or Clomed)

Weak anti-estrogen, dynamically restores libido and natural testosterone production. The most common drug in PCT. Turinabol can be used after methandrostinolone or any type of steroid including methane, propionate, nandrolone, decane or deca, donabol, sustanon or susta, boldenone, stanozolol. Doses and duration of administration depend on the doses and duration of the AS course. Consider three common options:

  1. For PCT after light courses (for example, 50-100 tablets of Methane (Danabol) or Stanozolol, Turinabol, Oxandrolone, Testosterone Propionate) 100 mg of the drug (2 tablets) per day for 5-7 days and 50 mg for 10 – 12 days are enough.
  2. After cycles of about 1.5-2.5 months with multiple drugs, we get 12-14 days for PCT for 100 mg clomiphene and 15-20 days for 50 mg clomiphene.
  3. For heavy high doses lasting more than 2 months and containing three or more drugs, take 150 mg (3 tablets) for 3 days, followed by 100 mg for 15 days and 50 mg for 20 days.

See info about your first steroid cycle


A powerful anti-estrogen, but restoring natural testosterone levels helps less.

It is commonly used as an anti-estrogen during AS at a dose of 20 mg per day.

CAUTION! Tamoxifen should not be used during or after a cycle with progesterone drugs such as nandrolone, trenbolone, oxymethalone (Anadrol). Increases the effect of progesterone and thus the side effects !!!

You can use the dose after other medicines with a light course:

  • 80 mg on the first day.
  • 7-10 days for 40 mg.
  • Another 15 days at 20mg.


powerful anti-estrogen used in the cycle and 2-3 weeks later. The drug prevents the aromatization reaction (conversion of excess testosterone into estrogen), as well as side effects, including gynecomastia.

The average dose is 0.5-1 mg per day.

Read also about tamoxifen vs clomid


Powerful aromatase inhibitor. The drug restores LH, FSH and naturally increases testosterone production. Used both during and after class. It treats gynecomastia well and gets rid of it quickly. It is recommended not to overdose as it reduces estradiol to zero which is not good and reduces libido.


Antiestrogens block the aromatization reaction, increase libido. Since Proviron is an androgen and somewhat inhibits “natural” testosterone production, you should use it at the end of the course or before PCT.

Dosage 50 mg per day, preferably divided into 2 times.


Reduces prolactin levels, should be used with active progesterone drugs such as Trenbolone and Nandrolone (Deca). Perfectly fights gynecomastia, restores libido and increases testosterone production.

The average dose of cabergoline is 0.5-1 mg per week.

Additional medication

Cortisol is reduced by anti-catabolics such as:

  • a growth hormone;
  • Insulin;
  • Clenbuterol

They are used throughout the course as well as in the PCT.